Brief on clinical trials

A research trial is a carefully organized study testing how a new treatment or a new drug works on humans. Research experiments are also called clinical trials or clinical studies. “Clinical” because it takes place in the clinic and not in the laboratory. A clinical trial is described in a protocol, which is a 100-130-page detailed description of the trial. The key questions that must always be answered:

  • How well does the tested drug work?
  • Is it more effective than the current treatment?
  • Is it safe and are there any side effects?

All clinical trials must be approved in advance by the Bristish Medicines & Healthcare Products Regulatory Agency and by the Ethics Committee. Clinical trials can take place in 4 phases. Members of the Research Panel are invited to participate in Phases 2, 3 and 4.

Phase 1: The first time the drug is tested on humans. Typically, on a small group of healthy individuals (20-80 people). Phase 1 examines the safety of the drug, how it breaks down in the body as well as its effects and side effects.

Phase 2: The trials are performed on a group of patients suffering from the disease to which the drug is directed. Here, typically, 100-300 people participate. The purpose of the study is to investigate how effective the new drug is and to determine the dosage.

Phase 3: These trials include many patients with the relevant disease, typically 500-10,000. The new drug is directly tested against similar existing preparations on the market. The treatment effect and dosage are finally tested and side effects monitored. Phase 3 trials often take place over 2-3 years. Based on the results, the pharmaceutical company submits an application to the authorities for authorization to bring the drug to the market.

Phase 4: These trials take place after the drug has been on the market. Here, a significant number of people receive the new treatment and investigations are conducted into whether there are other risks, new uses or very rare side effects.

Why participate in research?

Clinical research is entirely dependent on patients’ involvement in developing and testing new medications and new therapies. All drugs have been tested on humans before being released for more general use.

In short, there are 6 good reasons to participate in clinical research:

  • You contribute to the development of new medications and treatments for new generations of people with the same disease as yourself.
  • You will have the opportunity to try out the latest treatments at no cost.
  • You ensure that medical research and development are maintained at British hospitals, enabling doctors to offer new treatments to British patients.
  • You will be followed by highly specialized medical teams and receive extraordinary care.
  • You will obtain thorough knowledge about your own illness and how to manage it.
  • Your travel expenses will be covered, and in some cases financial compensation will be offered for your participation.

Frequently Asked Questions

Is my information kept safe

British Research Panel is approved by the Data Inspection Agency and complies with the strictest requirements for data security and storage.

Is it free to be a member of British Research Panel?

Yes, it does not cost anything to be a member of British Research Panel.

What is a clinical trial?

A clinical trial or study investigates how a new medicine or treatment works on humans. It investigates the effects of the medication and if there are any side effects.
Clinical trials are conducted in 4 phases.

Does it cost anything to participate in a clinical trial?

No, it’s always free to participate and all medicine and examinations are free of charge.

Will the study cover my costs and loss of wages?

Yes, you will always receive compensation for your travel costs. You will also in most cases receive compensation if a clinical visit or an examination is extended.

Can I unsubscribe from British Research Panel?

Yes, you can unsubscribe from British Research Panel at any time. This will delete all of your information.

Can I change my mind about participation in a research study?

Yes, you can change your mind and withdraw from the study at any time.

How will I be contacted by British Research Panel, and how often will I be contacted?

As a member, you will only hear from British Research Panel when there is a new research study that matches your health profile and takes place at a nearby hospitals.
We start by sending you an email or an SMS, where you can read more about the study.

Where do the tests take place?

All research studies are conducted at British public hospitals and clinics. Specialist doctors and nurses are responsible for the treatment and investigations in the designated research clinics and centres.

How long does the trial run and how many visits do I have to plan?

Most studies have a duration of 1-2 years. There are 3-4 visits initially, in order to conduct thorough examinations, followed by routine visits, typically every 4 months.

What is placebo?

Placebo is an inactive preparation, a calcium tablet. In some studies, placebo is given to a small portion of participants, to exclude the positive effect that occurs in people, when participating in an experiment and receiving special care and monitoring. Neither doctors nor participants know whether they receive placebo or the active substance. This is called double-blind study.